The Heart of Power – Episode 10: When the Moon and Stars Fell on One Man

It was late afternoon, April 12, 1945. Harry Truman had just settled into his Senate office when the phone rang. He was told to come to the White House at once.
When he arrived, Eleanor Roosevelt was waiting. Her face was pale, her words simple: “Harry, the President is dead.”
Truman staggered. “Is there anything I can do for you?” he asked.
Eleanor shook her head. “Is there anything we can do for you? For you are the one in trouble now.”
The words hit harder than any diagnosis…..

The Tyranny of the Average: Why Medicine Struggles With the Individual

He sits across from me, his file glowing on the computer screen. Numbers everywhere: cholesterol edging upward, blood pressure leaning north, a family tree littered with cardiac potholes.
He leans forward, eyes narrowing.
“So, doctor—what are my chances?”
I recite the liturgy: statins cut relative risk by about 25%, blood pressure control lowers stroke risk by 30–40%. Add them up, and the curves bend favorably.
He doesn’t look reassured.
“Yes, but will it happen to me—or not?”

Medicating Appetite: The GLP-1 Dilemma

At first, they were diabetes drugs.
GLP-1 receptor agonists—liraglutide, semaglutide, and later tirzepatide—were developed to help patients with type 2 diabetes regulate blood sugar. They mimicked a gut hormone, GLP-1, that modulates insulin, glucagon, and gastric emptying. They also acted on the brain.
Appetite went down.
Weight came off.
And people noticed.