The Lipid Hypothesis – Closing in on the Truth

Today was a big day at the annual conference of the American Heart Association in Chicago. The results of the long and eagerly awaited IMPROVE-IT trial were presented. You may think IMPROVE-IT is just another ordinary study of the efficacy of a particular cholesterol lowering drug. But it’s more than that because it tests the important and heavily debated lipid … Read more

HDL Cholesterol – The “Good” Cholesterol Explained

High-density lipoprotein cholesterol (HDL cholesterol) is commonly measured to assess the risk of heart disease. If you’ve had a blood sample drawn for assessment of lipid panel you probably already know if your cholesterol level is acceptable or not. You might also recall something about good and bad cholesterol and the ratio between these two. Of course, … Read more

Statins, Statistics and Statinistics

Current medical knowledge is to a large extent based on results from scientific studies. Traditionally, these results are published in peer-reviewed medical journals. Before being accepted, a scientific paper has to go through critical assessment by expert reviewers who will assess the paper’s suitability for publication. The peer review process is intended to guarantee standards of quality and … Read more

Can Further Lowering of Blood Cholesterol Save Lives?

For many years, lowering blood levels of low density lipoprotein cholesterol (LDL-C) has been a key target for individuals with cardiovascular disease (CVD) and healthy people at increased risk for developing such disease. Statin drugs play a key role for risk reduction and are prescribed to millions of people worldwide. Apart from lowering blood cholesterol, … Read more

The Side Effects of Statins

One of the biggest questions facing clinical cardiology today is the decision on when to treat healthy people with statin drugs. Data from randomized clinical trials show that such treatment may be beneficial for individuals with high risk of developing cardiovascular disease. However, statins are not without side effects, therefore we have to be sure … Read more

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